gene mutation acts like a document with pages glued together in a photocopier

Categories: Comparisons

An example of an analogy used in popular science writing:

"A normal gene contains from five to 30 GAA repeats but a mutated gene contains from 70 up to 1,000 repeated GAA motifs. … The big GAA expansion acts as a 'sticky' region, which prevents good copying of the DNA. It's analogous to trying to photocopy a 50-page document, when pages four to twelve have been glued together. They won't feed into the copier, and the process grinds to a halt, for that particular document. In the case of the Freidreich's ataxia gene, no copying means no RNA, which means no protein."

Nessa Carey (2015) Junk DNA. A journey through the dark matter of the genome. London: Icon Books Ltd.

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Many examples of science analogies are listed in 'Creative comparisons: Making science familiar through language. An illustrative catalogue of figurative comparisons and analogies for science concepts'. Free Download.

Author: Keith

Former school and college science teacher, teacher educator, research supervisor, and research methods lecturer. Emeritus Professor of Science Education at the University of Cambridge.