antigen to antibody is not like paint to wall

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Categories: Comparisons

An historical example of an analogy used by a scientist:

Bordet* said that just because twice as much serum is needed to combine with two as with one dose of bacterial emulsion, some bacteriologists argue that antigen and antibody must combine according to a law of definite proportions. That, he said scornfully, was like claiming that paint must react in definite proportions with a wall. The regular chemical law of definite proportions need not apply.

Pauline M. H. Mazumdar

Mazumdar, P. M. H. History of Immunology. In W. E. Paul (Ed.), Fundamental Immunology (5th ed.). Lippincott Williams & Wilkins Publishers.

* Jules Bordet {1870-1961}, immunologist, Nobel laureate

[Please be aware that a word may have different nuances, or even a different meaning, according to context.]« Back to Index

Author: Keith

Former school and college science teacher, teacher educator, research supervisor, and research methods lecturer. Emeritus Professor of Science Education at the University of Cambridge.