ignoring modest initial differences in experimental studies is like considering polar compounds as highly covalent

An example of an analogy drawing upon a chemical concept to explain another idea (from research methods, 'testing for initial equivalence'):

Table from book
From 'Chemical Pedagogy: : Instructional Approaches and Teaching Techniques in Chemistry'

"…many studies rely on testing for a statistically significant difference, although this is a very dubious criterion for equivalence….

The results are analysed to see if there is a very unlikely difference between the scores in the different conditions. If a statistically significant difference is found, then this clearly suggests the groups cannot be considered equivalent. That is reasonable.

Unfortunately the reverse does not apply: if the differences do not reach significance, we cannot assume that implies equivalence. Say p=0.08 (which means that the differences were unlikely enough to only occur by chance about once in 12 times, rather than once in twenty times as when p=0.05), this still shows there was a difference that was unlikely to be down to random factors. There is a logical difference between what we are seeking to do in these two situations. In one case (comparing post-test results), we are trying to exclude all but those outcomes that are most unlikely to be chance events, and in the other (comparing pre-test scores), we are trying to show that any difference is small enough to be insignificant in affecting later outcomes. So, in the first case, we are trying to show something is very improbable, but in the other case, we are trying to show we have a very probable outcome. So, using the same kind of inferential test as a test of equivalence means (sensibly) excluding cases with very different pre-test outcomes across treatments from being labelled equivalent: but still (dubiously) admitting other substantially different pre-test outcomes across treatments as being equivalent.

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Many examples of science analogies are listed in 'Creative comparisons: Making science familiar through language. An illustrative catalogue of figurative comparisons and analogies for science concepts'. Free Download.

Glanvill, Joseph

Joseph Glanvill (1636 – 1680) was an English philosopher and priest. He supported the experimental method in science, and was a an early Fellow of the Royal Society. He encourages scepticism and argued against dogmatism, and was interested in the relationship between science and religion.

to captivate nature and make her subserve our purposes

An example of personification of nature in historical scientific writing, the

"If they, I say, confess the narrowness of human attainments, and dare not confide in the most plausible of their sentiments; if suck great and instructed spirits think we have not as yet phenomena enough to make as much as hypotheses; much less, to fix certain laws and prescribe methods to nature in her actings: what insolence is it then in the lesser size of mortals, who possibly know nothing but what they gleaned from some little system, or the disputes of men that love to swagger for opinions, to boast infallibility of knowledge, and swear they see the sun at midnight….

And perhaps human nature meets few more sweetly relishing and cleanly joys, than those, that derive from the happy issues of successful trials: yea, whether they succeed to the answering the particular aim of the naturalist or not; 'tis however a pleasant spectacle to behold the shifts, windings and unexpected caprichios of distressed nature, when pursued by a close and well managed experiment. …For 'tis a greater credit, if we judge by equal measures, to understand the art whereby the almighty wisdom governs the motions of the great automaton, and to know the ways of captivating nature, and making her subserve our purposes and designments; than to have learnt all the intrigues of policy, and the cabals of states and kingdoms; yea, then to triumph in the head of victorious troops over conquered empires. Those successes being more glorious which bring benefit to the world; then such ruinous ones as are dyed in human blood, and clothed in the livery of cruelty and slaughter."

Joseph Glanvill (1661) Scepsis Scientifica; or, The Vanity of Dogmatizing

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Many examples of personification are included in 'Creative comparisons: Making science familiar through language. An illustrative catalogue of figurative comparisons and analogies for science concepts'. Free Download.