The cell nucleus is probably bigger than an atomic nucleus

A cell is about ten times larger than an atom

Keith S. Taber

Dividing cell image by  ar130405 from Pixabay

Bert was a participant in the Understanding Science Project. Bert was interviewed in Y10 and asked about the topics he had been studying, which included circulation in biology, static electricity in physics, and oxidation in chemistry.

He talked about protons, electrons and atoms in both chemistry and physics, and was asked if this could also link with biology. Bert suggested that the nucleus comes up in chemistry (in the context of atomic structure) and physics (in the context of static electricity), and in biology in the context of cells (see 'The nucleus is the brain of the cell'). From the perspective of the science teacher, there is little basis for confusing the nucleus of an atom with that of a cell: obviously a cell is a complex entity with many components, each of which has itself a complex supra-molecular structure – so clearly the atomic nucleus is on a scale many orders of magnitude smaller than a cell nucleus.

However, the expert perspective is based on relating a lot of knowledge that the novice may not yet have, or at least, may not yet be coordinating. In Bert's case, he was only just starting to coordinate these ideas, as became clear when Bert was asked about the relative sizes of atomic and cell nuclei:

Which do you think is bigger, an atom or a cell, or are they both about the same size?

I'd say a cell.

A correct, but hardly confident and definitive, response. I followed up:

Which do you think is bigger, an atom or a cell, or are they both about the same size?

I'd say a cell.

So which do you think is bigger, the nucleus of a cell or the nucleus of an atom, or do you think they're both about the same size?

I think they're both about, well I should, oh. (Laughs) I'd say the one in the cell is probably bigger.

Why do you think that?

Well it's a cell, I'd have thought it was bigger than the atom. And you know, if the nucleus is kind of the main part of it, then it would probably be about, it would be the • same sort of – If the atom was brought to the size of the cell then the nucleus would be the same size I would have thought. So if the atom is smaller then the nucleus is a lot smaller.

I see, so you are sort of like scaling it, accordingly?

Yeah.

I see. So any idea roughly, just very roughly, how much bigger a cell is than an atom?

Erm oh, it's, they're both really microscopic so, I couldn't really say how much bigger they are than each other.

So it seems that Bert would "have thought [the cell] was bigger than the atom", but he did not seem entirely certain of this, whereas from the scientific perspective the difference in scale is considered vast and highly significant. Although cells are generally microscopic entries, they are more like familiar macroscopic objects that we can handle in everyday life than quanticles such as atoms which do not behave like familiar objects. (So, there is sense in which it is meaningless to talk about the size of atoms as they have no edges or surfaces but rather fade away to infinity.)

Erm oh, it's, they're both really microscopic so, I couldn't really say how much bigger they are than each other.

Mm. No, okay. So if I said a cell was ten times bigger than an atom, a hundred times bigger than an atom, a thousand times bigger than an atom?

I wouldn't say that, I'd say, I'd probably go with the first one you said, ten times bigger.

So roughly ten times bigger than an atom. So a nucleus of a cell you'd expect to be roughly ten times bigger than the nucleus of an atom?

Yeah.

But you're not really sure?

Well no, there are a lot more parts in a cell than there is in an atom. So I'd say the nucleus is… if they're both brought to the same size again, I'd say the nucleus of the atom would be bigger than the cell. But I could be totally wrong.

Oh I see, so you've got two arguments there. That because they, because they both have a nucleus in the middle, that in terms of scale, if the cell is quite a bit bigger than the atom, you'd expect the nucleus of the cell would be quite a bit bigger than the atom. But an atom is quite a simple structure, whereas a cell has a lot more things in it, it's a lot more complex.

Yeah.

So maybe there's not so much room for the nucleus of the cell as there is for an atom because you've got to fit so much more in.

Yeah.

Is that what you're thinking?

Yeah.

Bert's thinking here is quite reasonable, within the limits of his knowledge. He suggests that a cell nucleus will be larger than an atomic nucleus, because a cell is larger than an atom. However, he only think the cell nucleus will be about ten times the size of the atomic nucleus as he suspects the cell is only about ten times the size of an atom – after all they are both "really microscopic".

However, he also points out that a cell seems to have a more a lot more components to be fitted in, which would suggest that perhaps there is less space to fit the nucleus, so perhaps it would not be as much as ten times bigger than the atomic nucleus.

So Bert is able to consider a situation where there may be several factors at work (the size of the cell versus the size of the atom; the multitude of cellular components versus the sparsity of atoms) and appreciate how they would operate in an opposite sense within his argument so one could compensate for the other. (This type of thinking is needed a lot in studying science. One example is comparisons of ionisation enthalpies between different atoms and ions. I also recall physics objective examination questions that asked students to compare, say, the conductance of two wires with different resistivity, length and area.)

It is not reasonable to expect Bert to know just how much larger a typical cell nucleus is to an atomic nucleus, however, it is likely the science teacher would expect Bert to be aware that the nucleus is one small part of the atom, which is a constituent of the molecules and ions that are the chemical basis for the organelles such as nuclei found in cells. Bert had told me "there are lots of atoms in you", but he did not seem to have understood the role those atoms played in the structure of all tissues. This would seem to be an example of a fragmentation learning impediment, where a learner has not made the connections between topics and ideas that a science teacher would have intended and expected.

Do the forces from the outer shells push the protons and the neutrons together?

Keith S. Taber

Annie was a colearner (participant) in the Understanding Chemical Bonding project. In her first interview, during the first year of her two year 'A level' college course, Annie was asked about a (Bohr type) representation of a (sodium) atom. Annie did not know what held the protons and neutrons together in the atomic nucleus, but suggested it might be due to forces from the electrons "pushing":

Interviewer: Can you identify the different parts of that diagram? What's the blob in the centre?

Annie: It's the nucleus.

I: That's the nucleus. Do you know what's in the nucleus?

A: The protons and, no the electrons and the neutrons, no the protons and the neutrons. The electrons are round the outside.

I: There's protons and neutrons in the centre okay.

A: Yeah.

I: Erm, what holds them together, any idea?

A: Is it the forces from the outer ring? Outer rings or outer shells? The electronic forces?

I: What repelling them in? Holding them

A: Yeah.

I: in the centre? It could be.

A: Pushing them.

I: It's not actually, but that's a sensible suggestion. So you haven't actually done anything about what holds the nucleus together?

A: No.

The question of why the nucleons should be held together (given the repulsion between positive protons) is not usually considered in school chemistry lesson, and does not seem to be a question which students tend to spontaneously consider. The interview continued…

I: What holds the electrons in place?

(pause, c.4s)

A: Er (pause, c.9s) Not really sure, but I know there's a set pattern of how many can go in each shell, so if its connected with that?

I: Huh hm, do you think, do you think you need anything to hold the electrons in place, or I mean is it just the way the Universe is, or God's will, or, you know, or just aesthetic, you know nature's aesthetic,

A: Yeah.

I: and it looks pretty? I mean do you think there has to be some physical reason why the electrons are there rather than anywhere else?

A: Probably is to do with the structure of it.

I: But you are not, you're not sure why,

A: No.

I: it should be that the electrons should be in orbitals or orbits?

A: No.

I: Rather than just scattered higgledy-piggledy.

A: No, I don't know that.

In this section of the interview, Annie seems to suggest she is not aware of any forces acting on the electrons, and suggests it may be something inherent in the electronic structure which holds the electrons in place. It seems odd that Annie does not invoke a force from the nucleus, given her comment just earlier about a possible pushing from the outer electron ring/shell onto the nucleons. It seems Annie does not know about, or at least does not bring to mind, an electrical force attracting the electrons and nucleus. However, this was tested by a slightly different question…

Okay. So can you tell me why the electrons don't fall out of the atom? I mean if you imagine that this was sort of, er, an atom that's placed vertically, why don't the electron's just fall out of the bottom?

A: The forces hold them together.

I: What kind of forces are they. Do you know?

(pause, c.5s)

A: The attraction from the nucleus, from the protons.

I: So the protons in the nucleus attract the electrons?

A: Yeah.

I: So what kind of attraction is that. What kind of force is that?

A: Er (pause, c.7s) I don't know

So Annie is aware that the electrons are attracted by the nucleus, and specifically by the protons. Despite this, Annie does not suggest the interaction is electronic, or specially refer to charge. Her suggestion that the outer electron shell may push on the nucleus, holding it together, contradicts Newton's third law in that forces between bodies are either attractive or repulsive, not not a mixture of the two. So if the nucleus attracts electrons, then electrons must attract (not push) the nucleus. Annie's suggestion was also inconsistent with the way forces between charges depend upon separation (by an inverse square law): the repulsion between adjacent protons would be far larger than any force due to the more distant electrons.